Endocrine Abstracts

Autoimmune thyroid diseases (AITD), such as Hashimoto’s thyroiditis (HT) and Grave’s disease (GD) frequently form overlap syndromes with rheumatoid arthritis (RA). Among genetic factors, the role of the HLA antigens and CTLA4 gene polymorphisms in the formation of such overlap syndromes has been suggested.Objective: Aim of this study was to investigate the alleli and genotypes frequency of the CTLA4 exon1 A49G polymorphism in Slovak patients wi...